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TC-S 7005 Chemical Structure

TC-S 7005

Data Sheet For research use only. Not for human use.
Cat. No. :BCP48202CAS No. :1082739-92-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1082739-92-1 Cat. No. BCP48202
Name TC-S 7005
Synonyms TC S 7005; TCS 7005; TCS-7005; TCS7005;
SMILES CC(C1=CC=CC=C1)NC2=NC=C3C(=C2)C(=NO3)C4=CC5=C(C=C4)OCO5
Chemical Name
Formula C21H17N3O3 M. Wt 359.38
Purity 98% Storage Store at 4-8°C
Description TC-S 7005 is a potent and selective polo-like kinase 2 (PLK2) inhibitor (IC50 = 4 nM). TC-S 7005 shows selectivity for PLK2 over PLK3 and PLK1 (IC50 values are 24 and 214 nM respectively). TC-S 7005 induces mitotic arrest and cell death in HCT 116 colorectal cells.
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