磷酰胺氮芥
CAS号 | 10159-53-2 | 货号 | BCP48451 |
中文名 | 磷酰胺氮芥 | ||
英文名 | Phosphoramide mustard | ||
中文别名 | |||
英文别名 | Friedman acid;Phosphorodiamidic mustard; | ||
分子式 | C4H11Cl2N2O2P | 分子量 | 221.02 |
生物活性 | Phosphoramide Mustard is one of a number of chemically-related alkylating agents with antineoplastic properties. The prototype of this group of agents is cyclophosphamide. Most phosphoramide mustards are administered as prodrugs that undergo reductive activation in hypoxic environments to yield cytotoxic metabolites. These agents alkylate and crosslink DNA, resulting in inhibition of DNA replication. Phosphoramide mustards are also immunosuppressants, mutagens and teratogens. | ||
信号通路 | Cell Cycle/DNA Damage | ||
靶 点 | DNA Alkylator/Crosslinker |
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服:
- 全国免费电话:400-099-8200
瀚香生物(Biochempartner) 的所有产品和服务仅用于科学研究,禁止用于人体和治疗!