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Phosphoramide mustard 结构式

磷酰胺氮芥

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货号 :BCP48451CAS号 :10159-53-2纯度:98%
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  • 基本信息与产品描述
CAS号 10159-53-2 货号 BCP48451
中文名 磷酰胺氮芥
英文名 Phosphoramide mustard
中文别名
英文别名 Friedman acid;Phosphorodiamidic mustard;
SMILES C(CCl)N(CCCl)P(=O)(N)O
化学名称
分子式 C4H11Cl2N2O2P 分子量 221.02
纯度 98% 配送 惯例下常温包邮
产品描述 Phosphoramide Mustard is one of a number of chemically-related alkylating agents with antineoplastic properties. The prototype of this group of agents is cyclophosphamide. Most phosphoramide mustards are administered as prodrugs that undergo reductive activation in hypoxic environments to yield cytotoxic metabolites. These agents alkylate and crosslink DNA, resulting in inhibition of DNA replication. Phosphoramide mustards are also immunosuppressants, mutagens and teratogens.
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