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CAS号 | 10159-53-2 | 货号 | BCP48451 |
中文名 | 磷酰胺氮芥 | ||
英文名 | Phosphoramide mustard | ||
中文别名 | |||
英文别名 | Friedman acid;Phosphorodiamidic mustard; | ||
SMILES | C(CCl)N(CCCl)P(=O)(N)O | ||
化学名称 | |||
分子式 | C4H11Cl2N2O2P | 分子量 | 221.02 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Phosphoramide Mustard is one of a number of chemically-related alkylating agents with antineoplastic properties. The prototype of this group of agents is cyclophosphamide. Most phosphoramide mustards are administered as prodrugs that undergo reductive activation in hypoxic environments to yield cytotoxic metabolites. These agents alkylate and crosslink DNA, resulting in inhibition of DNA replication. Phosphoramide mustards are also immunosuppressants, mutagens and teratogens. |
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