MID-1

  • Chemical Properties
CAS No. 312608-54-1 Cat. No. BCP48931
Name MID-1
Synonyms MID1;MID 1;
Formula C12H11N3O4S M. Wt 293.3
  • Biological Activity
Description MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets Insulin Receptor 

Structure

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