MID-1
CAS No. | 312608-54-1 | Cat. No. | BCP48931 |
Name | MID-1 | ||
Synonyms | MID1;MID 1; | ||
Formula | C12H11N3O4S | M. Wt | 293.3 |
Description | MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | Insulin Receptor |
Structure
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