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CAS No. | 312608-54-1 | Cat. No. | BCP48931 |
Name | MID-1 | ||
Synonyms | MID1;MID 1; | ||
SMILES | CCOC1=CC=C(C=C1)C(=O)NC2=NC=C(S2)[N+](=O)[O-] | ||
Chemical Name | |||
Formula | C12H11N3O4S | M. Wt | 293.3 |
Purity | 98% | Storage | Store at 4-8°C |
Description | MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake. |
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