Lazabemide hydrochloride
| CAS No. | 103878-83-7 | Cat. No. | BCP48943 |
| Name | Lazabemide hydrochloride | ||
| Synonyms | Lazabemide HCl;Ro 19-6327 hydrochloride; | ||
| Formula | C8H10ClN3O.HCl | M. Wt | 236.10 |
| Description | Lazabemide hydrochloride is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM) but less active for MAO-A (IC50>100 μM). Lazabemide inhibits monoamine uptake at high concentrations, the IC50 values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease. | ||
| Pathways | Neuro Signaling Pathway | ||
| Targets | Monoamine Oxidase | ||
Structure
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