Lazabemide hydrochloride New
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CAS No. | 103878-83-7 | Cat. No. | BCP48943 |
Name | Lazabemide hydrochloride | ||
Synonyms | Lazabemide HCl;Ro 19-6327 hydrochloride; | ||
SMILES | C1=CC(=NC=C1Cl)C(=O)NCCN.Cl | ||
Chemical Name | |||
Formula | C8H10ClN3O.HCl | M. Wt | 236.10 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Lazabemide hydrochloride is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM) but less active for MAO-A (IC50>100 μM). Lazabemide inhibits monoamine uptake at high concentrations, the IC50 values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease. |
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