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Lazabemide hydrochloride Chemical Structure

Lazabemide hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP48943CAS No. :103878-83-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 103878-83-7 Cat. No. BCP48943
Name Lazabemide hydrochloride
Synonyms Lazabemide HCl;Ro 19-6327 hydrochloride;
SMILES C1=CC(=NC=C1Cl)C(=O)NCCN.Cl
Chemical Name
Formula C8H10ClN3O.HCl M. Wt 236.10
Purity 98% Storage Store at 4-8°C
Description Lazabemide hydrochloride is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM) but less active for MAO-A (IC50>100 μM). Lazabemide inhibits monoamine uptake at high concentrations, the IC50 values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease.
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