Enzastaurin Hydrochloride
CAS No. | 359017-79-1 | Cat. No. | BCP49012 |
Name | Enzastaurin Hydrochloride | ||
Synonyms | Enzastaurin HCl; LY317615 HCl; LY 317615 HCl; LY-317615 HCl; | ||
Formula | C32H29N5O2.ClH | M. Wt | 552.08 |
Description | Enzastaurin Hydrochloride is the hydrochloride salt of enzastaurin, a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden. | ||
Pathways | Epigenetics | ||
Targets | PKC |
Structure
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