Enzastaurin Hydrochloride

  • Chemical Properties
CAS No. 359017-79-1 Cat. No. BCP49012
Name Enzastaurin Hydrochloride
Synonyms Enzastaurin HCl; LY317615 HCl; LY 317615 HCl; LY-317615 HCl;
Formula C32H29N5O2.ClH M. Wt 552.08
  • Biological Activity
Description Enzastaurin Hydrochloride is the hydrochloride salt of enzastaurin, a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.
Pathways Epigenetics 
Targets PKC 

Structure

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