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Enzastaurin Hydrochloride Chemical Structure

Enzastaurin Hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP49012CAS No. :359017-79-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 359017-79-1 Cat. No. BCP49012
Name Enzastaurin Hydrochloride
Synonyms Enzastaurin HCl; LY317615 HCl; LY 317615 HCl; LY-317615 HCl;
SMILES CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)C6CCN(CC6)CC7=CC=CC=N7.Cl
Chemical Name
Formula C32H29N5O2.ClH M. Wt 552.08
Purity 98% Storage Store at 4-8°C
Description Enzastaurin Hydrochloride is the hydrochloride salt of enzastaurin, a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.
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