MGH-CP1
| CAS No. | 896657-58-2 | Cat. No. | BCP49045 |
| Name | MGH-CP1 | ||
| Synonyms | MGHCP1; MGH CP1; | ||
| Formula | C20H24N4OS | M. Wt | 368.49 |
| Description | MGH-CP1 is a potent and orally active TEAD2 and TEAD4 auto-palmitoylation inhibitor with IC50s of 710 nM and 672 nM, respectively. MGH-CP1 can decrease the palmitoylation levels of endogenous or ectopically expressed TEAD proteins in cells. MGH-CP1 can suppress Myc expression, inhibit epithelial over-proliferation, and induce apoptosis when together with Lats1/2 deletion. | ||
| Pathways | Apoptosis Pathway | ||
Structure
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