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MGH-CP1 Chemical Structure

MGH-CP1

Data Sheet For research use only. Not for human use.
Cat. No. :BCP49045CAS No. :896657-58-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 896657-58-2 Cat. No. BCP49045
Name MGH-CP1
Synonyms MGHCP1; MGH CP1;
SMILES C1C2CC3CC1CC(C2)(C3)C4=CC=C(C=C4)NC(=O)CSC5=NC=NN5
Chemical Name
Formula C20H24N4OS M. Wt 368.49
Purity 98% Storage Store at 4-8°C
Description MGH-CP1 is a potent and orally active TEAD2 and TEAD4 auto-palmitoylation inhibitor with IC50s of 710 nM and 672 nM, respectively. MGH-CP1 can decrease the palmitoylation levels of endogenous or ectopically expressed TEAD proteins in cells. MGH-CP1 can suppress Myc expression, inhibit epithelial over-proliferation, and induce apoptosis when together with Lats1/2 deletion.
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