PXL-770

  • Chemical Properties
CAS No. 1523493-53-9 Cat. No. BCP49199
Name PXL-770
Synonyms PXL 770;PXL770;
Formula C23H18ClNO3S M. Wt 423.91
  • Biological Activity
Description PXL770 is a novel orally bioavailable, small-molecule direct AMPK activator with EC50 of 16.2, 42.1 and 64 nM for α1β1γ1, α1β1γ2 and α1β1γ3, directly increases AMPK activity by both allosteric activation and protection from dephosphorylation.
Pathways PI3K/Akt/mTOR Epigenetics 
Targets AMPK 

Structure

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