PXL-770
CAS No. | 1523493-53-9 | Cat. No. | BCP49199 |
Name | PXL-770 | ||
Synonyms | PXL 770;PXL770; | ||
Formula | C23H18ClNO3S | M. Wt | 423.91 |
Description | PXL770 is a novel orally bioavailable, small-molecule direct AMPK activator with EC50 of 16.2, 42.1 and 64 nM for α1β1γ1, α1β1γ2 and α1β1γ3, directly increases AMPK activity by both allosteric activation and protection from dephosphorylation. | ||
Pathways | PI3K/Akt/mTOR Epigenetics | ||
Targets | AMPK |
Structure
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