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CAS No. | 1523493-53-9 | Cat. No. | BCP49199 |
Name | PXL-770 | ||
Synonyms | PXL 770;PXL770; | ||
SMILES | C1CCC2=C(C1)C=CC(=C2O)C3=C(SC4=C3C(=C(C(=O)N4)C5=CC=CC=C5)O)Cl | ||
Chemical Name | |||
Formula | C23H18ClNO3S | M. Wt | 423.91 |
Purity | 98% | Storage | Store at 4-8°C |
Description | PXL770 is a novel orally bioavailable, small-molecule direct AMPK activator with EC50 of 16.2, 42.1 and 64 nM for α1β1γ1, α1β1γ2 and α1β1γ3, directly increases AMPK activity by both allosteric activation and protection from dephosphorylation. |
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