Cbl-b-IN-3

  • Chemical Properties
CAS No. 2573775-59-2 Cat. No. BCP49568
Name Cbl-b-IN-3
Synonyms
Formula C30H34F3N5O M. Wt 537.62
  • Biological Activity
Description Cbl-b-IN-3 is a casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) inhibitor with an IC50 of < 1 nM. Cbl-b is an E3 ubiquitin ligase that negatively regulates T-cell activation.
Pathways Protease/Metabolic Enzyme 
Targets E1 E2 E3 Enzyme 

Structure

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