Cbl-b-IN-3 New
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CAS No. | 2573775-59-2 | Cat. No. | BCP49568 |
Name | Cbl-b-IN-3 | ||
Synonyms | |||
SMILES | CC1CCCN(C1)CC2=CC3=C(CN(C3=O)C4=CC=CC(=C4)C5(CC(C5)C)C6=NN=CN6C)C(=C2)C(F)(F)F | ||
Chemical Name | |||
Formula | C30H34F3N5O | M. Wt | 537.62 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Cbl-b-IN-3 is a casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) inhibitor with an IC50 of < 1 nM. Cbl-b is an E3 ubiquitin ligase that negatively regulates T-cell activation. |
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