MS023 dihydrochloride

  • Chemical Properties
CAS No. 1992047-64-9 Cat. No. BCP49591
Name MS023 dihydrochloride
Synonyms MS023 2HCl;MS-023 dihydrochloride;MS 023 dihydrochloride;
Formula C17H27Cl2N3O M. Wt 360.3
  • Biological Activity
Description MS 023 dihydrochloride is a potent and selective type I PRMT inhibitor (IC50 values are 8, 8, 30, 83 and 119 nM for PRMT6, PRMT8, PRMT1, PRMT4 and PRMT3, respectively). Exhibits no significant activity against type II and III PRMTs, PKMTs, DNMTs, KDMs and reader proteins. Reduces global arginine asymmetric dimethylation levels in vitro. Also inhibits and reduces TGF-β-activated kinase 1 expression and protein levels.
Pathways Epigenetics 
Targets Histone Methyltransferase 

Structure

Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
Service & Tech Support:orders@biochempartner.com
Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.