MS023 dihydrochloride New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1992047-64-9 | Cat. No. | BCP49591 |
| Name | MS023 dihydrochloride | ||
| Synonyms | MS023 2HCl;MS-023 dihydrochloride;MS 023 dihydrochloride; | ||
| SMILES | CC(C)OC1=CC=C(C=C1)C2=CNC=C2CN(C)CCN.Cl.Cl | ||
| Chemical Name | |||
| Formula | C17H27Cl2N3O | M. Wt | 360.3 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | MS 023 dihydrochloride is a potent and selective type I PRMT inhibitor (IC50 values are 8, 8, 30, 83 and 119 nM for PRMT6, PRMT8, PRMT1, PRMT4 and PRMT3, respectively). Exhibits no significant activity against type II and III PRMTs, PKMTs, DNMTs, KDMs and reader proteins. Reduces global arginine asymmetric dimethylation levels in vitro. Also inhibits and reduces TGF-β-activated kinase 1 expression and protein levels. | ||
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