Mifamurtide sodium hydrate

  • Chemical Properties
CAS No. 838853-48-8 Cat. No. BCP49623
Name Mifamurtide sodium hydrate
Synonyms MTP-PE sodium hydrate; L-MTP-PE sodium hydrate; CGP 19835 sodium hydrate; CGP19835 sodium hydrate; CGP-19835 sodium hydrate;
Formula C59H110N6NaO20P M. Wt 1277.51
  • Biological Activity
Description Mifamurtide sodium hydrate is the sodium hydrate of mifamurtide. Mifamurtide is a liposomal formulation containing a muramyl dipeptide (MDP) analogue with potential immunomodulatory and antineoplastic activities. Muramyl tripeptide phosphatidylethanolamine (MTP-PE), a derivative of the mycobacterial cell wall component MDP, activates both monocytes and macrophages. Activated macrophages secrete cytokines and induce the recruitment and activation of other immune cells, which may result in indirect tumoricidal effects. Liposomal encapsulation of MTP-PE prolongs its half-life and enhances tissue targeting.
Pathways Others Pathway 
Targets NLR 

Structure

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