Mifamurtide sodium hydrate New
Data Sheet
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| CAS No. | 838853-48-8 | Cat. No. | BCP49623 |
| Name | Mifamurtide sodium hydrate | ||
| Synonyms | MTP-PE sodium hydrate; L-MTP-PE sodium hydrate; CGP 19835 sodium hydrate; CGP19835 sodium hydrate; CGP-19835 sodium hydrate; | ||
| SMILES | CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCCNC(=O)[C@H](C)NC(=O)CC[C@H](C(=O)N)NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@H]([C@H](C=O)NC(=O)C)[C@@H]([C@@H](CO)O)O)OC(=O)CCCCCCCCCCCCCCC.O.[Na+] | ||
| Chemical Name | |||
| Formula | C59H110N6NaO20P | M. Wt | 1277.51 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Mifamurtide sodium hydrate is the sodium hydrate of mifamurtide. Mifamurtide is a liposomal formulation containing a muramyl dipeptide (MDP) analogue with potential immunomodulatory and antineoplastic activities. Muramyl tripeptide phosphatidylethanolamine (MTP-PE), a derivative of the mycobacterial cell wall component MDP, activates both monocytes and macrophages. Activated macrophages secrete cytokines and induce the recruitment and activation of other immune cells, which may result in indirect tumoricidal effects. Liposomal encapsulation of MTP-PE prolongs its half-life and enhances tissue targeting. | ||
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