RMC-7977
| CAS No. | 2765082-12-8 | Cat. No. | BCP49669 |
| Name | RMC-7977 | ||
| Synonyms | RMC 7977;RMC7977; | ||
| Formula | C47H60N8O6S | M. Wt | 865.1 |
| Description | RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants.RMC-7977 can lead to tumor regressions and was well tolerated in diverse RAS-addicted preclinical cancer models. RMC-7977 also can inhibit the growth of KRASG12C cancer models. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Ras/Rho | ||
Structure
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