ML 161
| CAS No. | 423735-93-7 | Cat. No. | BCP08413 |
| Name | ML 161 | ||
| Synonyms | ML161;ML-161; | ||
| Formula | C17H17BrN2O2 | M. Wt | 361.23 |
| Description | ML-161 displays dose-dependent inhibition of thrombin-induced platelet activation, as measured by P-selectin expression. ML-161 displays selective inhibition of SFLLRN and thrombin-induced platelet aggregation, both of which operate via PAR1, and has no effect on AYPGKF, thromboxane, or ADP-induced platelet aggregation, which are all agonists at alternative platelet GPCRs. | ||
| Pathways | GPCR/G Protein | ||
| Targets | PAR | ||
Structure
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