Home   >  
GPCR/G Protein
  >  
PAR

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

PAR

Chemical Structure Cat. No. Product Name CAS No.
SCH 79797 dihydrochloride Chemical Structure
 BCP46793 SCH 79797 dihydrochloride 1216720-69-2
SCH79797 dihydrochloride is a potent, selective non-peptide PAR1 receptor antagonist (IC50 = 70 nM). Inhibits haTRAP-induced- but not γ-thrombin-, ADP- or collagen-induced human platelet aggregation. Also selectively blocks PAR1 agonist- or thrombin-induced increases in cytosolic Ca2+ in vascular smooth muscle cells.
TRAP-6 Chemical Structure
 BCP34232 TRAP-6 141136-83-6
TRAP-6, a peptide compound, has been found to be a PAR1 agonist and could also influence the phosphorylation of rapid phosphodiesterase 3A in the positive way.
I-191 Chemical Structure
 BCP32684 I-191 1690172-25-8
I-191 is a potent, selective protease-activated receptor 2 (PAR2) antagonist.
SCH 79797 Chemical Structure
 BCP21206 SCH 79797 245520-69-8
SCH-79797 is a potent and selective PAR1 antagonist.
AC-264613 Chemical Structure
 BCP25509 AC-264613 1051487-82-1
AC-264613 is a novel potent, selective protease-activated receptor PAR2 agonist with potencies ranging from 30-100 nM.
Atopaxar Chemical Structure
 BCP05973 Atopaxar 751475-53-3;943239-67-6
Atopaxar, also known as E5555, is a potent and orally-active PAR-1 inhibitor.
Atopaxar hydrobromide Chemical Structure
 BCP25405 Atopaxar hydrobromide 474550-69-1
Atopaxar hydrobromide is a potent, reversible PAR-1 antagonist with IC50 of 19 nM.
AZ 3451 Chemical Structure
 BCP29277 AZ 3451 2100284-59-9
AZ 3451 is a potent, and selective PAR2 antagonist with Kd of 13.5 nM; shows excellent selectivity over PAR1 and PAR4 (>50 uM).
ML 161 Chemical Structure
 BCP08413 ML 161 423735-93-7
ML-161 is an allosteric inhibitor of PAR1.
FR171113 Chemical Structure
 BCP18806 FR171113 173904-50-2
FR 171113 is a protease-activated receptor 1 (PAR1) antagonist displaying significant antiplatelet activity in vitro.
12下一页共 14 条记录 1 / 2 页 
0086-13720134139