Norharmane
| CAS No. | 244-63-3 | Cat. No. | BCP20998 |
| Name | Norharmane | ||
| Synonyms | β-Carboline; 2-Azacarbazole; | ||
| Formula | C11H8N2 | M. Wt | 168.07 |
| Description | Norharmane is a β-Carboline alkaloid that is widespread in plants and animals, and frequently act as benzodiazepine inverse agonists. Norharmane showed a potent inhibition against α-glucosidase enzyme in a concentration dependent manner with an IC50 value of 0.27 mM for maltase and 0.41 mM for sucrase, respectively. A Lineweaver-Burk plot revealed that norharman inhibited α-glucosidase enzyme uncompetitively, with a Ki value of 0.13 mM. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | IDO | ||
Structure
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