Norharmane New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 244-63-3 | Cat. No. | BCP20998 |
| Name | Norharmane | ||
| Synonyms | β-Carboline; 2-Azacarbazole; | ||
| SMILES | C1=CC=C2C(=C1)C3=C(N2)C=NC=C3 | ||
| Chemical Name | |||
| Formula | C11H8N2 | M. Wt | 168.07 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Norharmane is a β-Carboline alkaloid that is widespread in plants and animals, and frequently act as benzodiazepine inverse agonists. Norharmane showed a potent inhibition against α-glucosidase enzyme in a concentration dependent manner with an IC50 value of 0.27 mM for maltase and 0.41 mM for sucrase, respectively. A Lineweaver-Burk plot revealed that norharman inhibited α-glucosidase enzyme uncompetitively, with a Ki value of 0.13 mM. | ||
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