5-氮杂胞嘧啶核苷
| CAS号 | 320-67-2 | 货号 | BCP07496 |
| 中文名 | 5-氮杂胞嘧啶核苷 | ||
| 英文名 | 5-Azacytidine | ||
| 中文别名 | |||
| 英文别名 | U18496; U-18496; U 18496;Ladakamycin; 5-AzaC; Azacitidine; | ||
| 分子式 | C8H12N4O5 | 分子量 | 244.2 |
| 生物活性 | 5-Azacytidine is a pyrimidine nucleoside analogue of cytidine with antineoplastic activity. Azacitidine is incorporated into DNA, where it reversibly inhibits DNA methyltransferase, thereby blocking DNA methylation. Hypomethylation of DNA by azacitidine may activate tumor suppressor genes silenced by hypermethylation, resulting in an antitumor effect. This agent is also incorporated into RNA, thereby disrupting normal RNA function and impairing tRNA cytosine-5-methyltransferase activity. | ||
| 信号通路 | Cell Cycle/DNA Damage Epigenetics | ||
| 靶 点 | DNA Methyltransferase Antimetabolite | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！