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DNA Methyltransferase

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DNA Methyltransferase

结构式 货号 产品名称 CAS号
Bobcat339 结构式
 BCP31159 Bobcat339 2280037-51-4
Bobcat339 is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2).
Bobcat339 hydrochloride 结构式
 BCP49654 Bobcat339 hydrochloride 2436747-44-1
Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of TET enzyme, with the IC50s of 33 μM and 73 μM for TET1 and TET2, respectively.
(R)-GSK-3685032 结构式
 BCP45844 (R)-GSK-3685032 2170140-50-6
(R)-GSK-3685032 is the R-enantiomer of GSK-3685032.
GSK3685032 TFA 结构式
 BCP45843 GSK3685032 TFA盐 GSK3685032TFA
GSK3685032, a potent first-in-class DNMT1-selective inhibitor that was shown via crystallographic studies to compete with the active-site loop of DNMT1 for penetration into hemi-methylated DNA between two CpG base pairs.
GSK3685032 结构式
 BCP43733 GSK3685032 2170137-61-6
GSK3685032, a potent first-in-class DNMT1-selective inhibitor that was shown via crystallographic studies to compete with the active-site loop of DNMT1 for penetration into hemi-methylated DNA between two CpG base pairs.
SW155246 结构式
 BCP37840 SW155246 420092-79-1
SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1) with IC50 value of 1.2 μM, displaying 30-fold selectivity for inhibition of human DNMT1 versus human or murine DNMT3A or -3B.
CM-272 结构式
 BCP32745 CM-272 1846570-31-7
CM-272 is a first-in-class reversible dual small molecule inhibitor against G9a and DNMTs in hematological malignancies.
Gamma-Oryzanol 结构式
 BCP13528 谷维素 11042-64-1
Gamma-Oryzanol is a triterpenoid.
Lomeguatrib 结构式
 BCP07818 罗米鲁曲 192441-08-0
Inhibitor of O6-methylguanine-DNA methyltransferase (MGMT); (IC50 = 0.009 μM in cell-free extracts from HeLa S3 cells); attenuates MGMT activity in vitro and in vivo.
Zebularine 结构式
 BCP12209 扎布拉林 3690-10-6
Zebularine(NSC309132; 4-Deoxyuridine) is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases, also inhibits cytidinedeaminase with Ki of 2 μM.
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