Halofuginone
| CAS No. | 55837-20-2 | Cat. No. | BCP07016 |
| Name | Halofuginone | ||
| Synonyms | Tempostatin;RU-19110;RU 19110;RU19110; | ||
| Formula | C16H17BrClN3O3 | M. Wt | 414.69 |
| Description | Halofuginone, also known as RU-19110, is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. | ||
| Pathways | TGF beta/Smad Wnt/Stem Cell | ||
| Targets | TGF β/Smad | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.