达泊西汀
| CAS号 | 119356-77-3 | 货号 | BCP21268 |
| 中文名 | 达泊西汀 | ||
| 英文名 | Dapoxetine | ||
| 中文别名 | 达帕西汀; | ||
| 英文别名 | LY-210448; LY 210448; LY210448; | ||
| 分子式 | C21H23NO | 分子量 | 305.42 |
| 生物活性 | Dapoxetine (LY-210448) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo. Alza submitted a NDA to the FDA for dapoxetine for the treatment of premature ejaculation in December 2004. In October 2005, the company received a FDA Non-Approvable letter from the FDA, at which time they planned to work with regulators to address outstanding questions. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | 5 HT Receptor/Serotonin Receptor | ||
结构式
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