首页   >  
Neuro Signaling Pathway
  • GPCR/G Protein
∨
  >  
5 HT Receptor/Serotonin Receptor

所有产品分类

所有产品

信号通路

研究领域

天然产物

抗体

多肽

催化剂

杂质对照品

医药中间体

基础原料

5 HT Receptor/Serotonin Receptor

结构式 货号 产品名称 CAS号
Pipamperone dihydrochloride 结构式
 BCP49191 哌帕潘二盐酸盐 2448-68-2
Pipamperone acts as an antagonist of the 5-HT2A, 5-HT2B, 5-HT2C D2, D3, D4, α1-adrenergic, and α2-adrenergic receptors. It shows much higher affinity for the 5-HT2A and D4 receptors over the D2 receptor (15-fold in the case of the D4 receptor, and even higher in the case of the 5-HT2A receptor), being regarded as "highly selective" for the former two sites at low doses. Pipamperone has low and likely insignificant affinity for the H1 and mACh receptors, as well as for other serotonin and dopamine receptors.
Temanogrel 结构式
 BCP24269 Temanogrel 887936-68-7
Temanogrel is a highly selective 5-HT2A receptor antagonist with a Ki of 4.9 nM.
NAS-181 methanesulfonate 结构式
 BCP49052 NAS-181 methanesulfonate 205242-62-2
NAS-181 methanesulfonate is a 5-HT(1B) receptor antagonist.
Sarizotan 结构式
 BCP24751 Sarizotan 351862-32-3
Sarizotan is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively.
Opiranserin 结构式
 BCP48961 Opiranserin 1441000-45-8
Opiranserin is a glycine transporter inhibitor and serotonin receptor antagonist. Opiranserin is a drug candidate.
DOI hydrochloride 结构式
 BCP25643 DOI hydrochloride 42203-78-1
DOI hydrochloride is a brain penetrant, mixed 5-HT2A/5-HT2C receptor agonist (Ki values are 0.7, 2.4 and 20 nM for 5-HT2A, 5-HT2C and 5-HT2B receptors respectively). Reduces rapid eye movement (REM) and slow wave sleep and increases waking in the rat. Hallucinogenic agent. Acts via 5-HT2A receptors to inhibit the inflammatory effects of tumor necrosis factor (TNF)-α.
8-OH-Dpat 结构式
 BCP25681 8-OH-Dpat 78950-78-4
8-OH-DPAT is a potent and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50 <5).
Prucalopride hydrochloride 结构式
 BCP48408 普卡必利盐酸盐 179474-80-7
Prucalopride hydrochloride is a selective 5-HT4 agonist.
RU-24969 结构式
 BCP48648 RU-24969 66611-26-5
RU-24969 is a potent, selective agonist of 5-HT1A and 5-HT1B receptors, with preference for 5-HT1B.
(Z)-Thiothixene 结构式
 BCP48214 (Z)-替沃噻吨 3313-26-6
Thiothixene is a modulator of human P-glycoprotein and is frequently used a an anti-psychotic.
123下一页末页共 270 条记录 1 / 27 页 
2853530910