Bay 11-7821
| CAS No. | 19542-67-7 | Cat. No. | BCP06798 |
| Name | Bay 11-7821 | ||
| Synonyms | BAY11-7082; BAY-11-7082; BAY 117082; BAY117082; BAY-11708; | ||
| Formula | C10H9NO2S | M. Wt | 207.25 |
| Description | BAY 11-7082 is an inhibitor of κB kinase (IKK) that has pharmacological activities that include anticancer, neuroprotective, and anti-inflammatory effects. BAY 11-7082 strongly suppressed the production of nitric oxide, prostaglandin E(2), and tumor necrosis factor-α and reduced the translocation of p65, major subunit of nuclear factor-κB, and its upstream signaling events such as phosphorylation of IκBα, IKK, and Akt. In addition. Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors.BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system. Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors. | ||
| Pathways | NFκB | ||
| Targets | IκB/IKK | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.