Bay 11-7821

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP06798CAS No. ：19542-67-7Purity：98%

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CAS No.	19542-67-7	Cat. No.	BCP06798
Name	Bay 11-7821
Synonyms	BAY11-7082; BAY-11-7082; BAY 117082; BAY117082; BAY-11708;
SMILES
Chemical Name
Formula	C10H9NO2S	M. Wt	207.25
Purity	98%	Storage	Store at 4-8°C
Description	BAY 11-7082 is an inhibitor of κB kinase (IKK) that has pharmacological activities that include anticancer, neuroprotective, and anti-inflammatory effects. BAY 11-7082 strongly suppressed the production of nitric oxide, prostaglandin E(2), and tumor necrosis factor-α and reduced the translocation of p65, major subunit of nuclear factor-κB, and its upstream signaling events such as phosphorylation of IκBα, IKK, and Akt. In addition. Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors.BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system. Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors.