Dapivirine

  • Chemical Properties
CAS No. 244767-67-7 Cat. No. BCP06491
Name Dapivirine
Synonyms TMC120; TMC 120; TMC-120; R 147681; R-147681; R147681;
Formula C20H19N5 M. Wt 329.4
  • Biological Activity
Description Dapivirine, also known as TMC120, is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promising drug candidates being used in topical microbicide products for prevention of HIV-1 sexual transmission.
Pathways Microbiology/Virology 
Targets Reverse Transcriptase HIV 

Structure

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