Dapivirine
CAS No. | 244767-67-7 | Cat. No. | BCP06491 |
Name | Dapivirine | ||
Synonyms | TMC120; TMC 120; TMC-120; R 147681; R-147681; R147681; | ||
Formula | C20H19N5 | M. Wt | 329.4 |
Description | Dapivirine, also known as TMC120, is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promising drug candidates being used in topical microbicide products for prevention of HIV-1 sexual transmission. | ||
Pathways | Microbiology/Virology | ||
Targets | Reverse Transcriptase HIV |
Structure
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