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CAS No. | 244767-67-7 | Cat. No. | BCP06491 |
Name | Dapivirine | ||
Synonyms | TMC120; TMC 120; TMC-120; R 147681; R-147681; R147681; | ||
SMILES | CC1=CC(=C(C(=C1)C)NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C | ||
Chemical Name | |||
Formula | C20H19N5 | M. Wt | 329.4 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Dapivirine, also known as TMC120, is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promising drug candidates being used in topical microbicide products for prevention of HIV-1 sexual transmission. |
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