U0126-EtOH
| CAS号 | 1173097-76-1 | 货号 | BCP05458 |
| 中文名 | U0126-EtOH | ||
| 英文名 | U0126-EtOH | ||
| 中文别名 | |||
| 英文别名 | U0126EtOH; U0126 EtOH;U0126 Ethanol;U0126.EtOH;UO126; U 0126; U-0126; | ||
| 分子式 | C18H16N6S2.C2H6O | 分子量 | 426.56 |
| 生物活性 | U0126.EtOH is an addition compound obtained by combining equimolar amounts of (2Z,3Z)-bis{amino[(2-aminophenyl)sulfanyl]methylidene}butanedinitrile (U0126) and ethanol. An inhibitor of mitogen-activated protein kinase that also exhibits anti-cancer properties. It has a role as an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor, an apoptosis inducer, an antineoplastic agent, an antioxidant, an osteogenesis regulator and a vasoconstrictor agent. It contains an U0126. | ||
| 信号通路 | MAPK Pathway | ||
| 靶 点 | MEK/ERK | ||
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A novel lead compound CM-118: Antitumor activity and new insight into the molecular mechanism and combination therapy strategy in c-Met- and ALK-dependent cancers
购于瀚香生物(Biochempartner)的U0126-EtOH(CAS:1173097-76-1)被引用 |
结构式
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