咪喹莫特
| CAS号 | 99011-02-6 | 货号 | BCP05151 |
| 中文名 | 咪喹莫特 | ||
| 英文名 | Imiquimod | ||
| 中文别名 | |||
| 英文别名 | S26308; S 26308 ; S26308; R837; R837; R 837; TMX-101; TMX 101; TMX101;Aldara;R 837;R-837;R837;Zyclara; | ||
| 分子式 | C14H16N4 | 分子量 | 240.3 |
| 生物活性 | Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist and is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod is a patient-applied cream used to treat certain diseases of the skin, including skin cancers (basal cell carcinoma, Bowen's disease, superficial squamous cell carcinoma, some superficial malignant melanomas, and actinic keratosis) as well as genital warts. However, Imiquimod is generally secondary to surgery, because surgery has a better chance to effectively treat at least some forms of skin cancer. It is known that imiquimod signals to the innate arm of the immune system through the toll-like receptor 7 (TLR7), commonly involved in pathogen recognition. Cells activated by imiquimod via TLR-7 secrete cytokines (primarily interferon-α (INF-α), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α)). | ||
| 上下游产品 | 99011-78-6（盐酸咪喹莫特） | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | TLR | ||
结构式
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