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Imiquimod 结构式

咪喹莫特

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货号 :BCP05151CAS号 :99011-02-6纯度:98%
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  • 基本信息与产品描述
CAS号 99011-02-6 货号 BCP05151
关联产品 99011-78-6(盐酸咪喹莫特)
中文名 咪喹莫特
英文名 Imiquimod
中文别名
英文别名 S26308; S 26308 ; S26308; R837; R837; R 837; TMX-101; TMX 101; TMX101;Aldara;R 837;R-837;R837;Zyclara;
SMILES CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
化学名称
分子式 C14H16N4 分子量 240.3
纯度 98% 配送 惯例下常温包邮
产品描述 Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist and is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod is a patient-applied cream used to treat certain diseases of the skin, including skin cancers (basal cell carcinoma, Bowen's disease, superficial squamous cell carcinoma, some superficial malignant melanomas, and actinic keratosis) as well as genital warts. However, Imiquimod is generally secondary to surgery, because surgery has a better chance to effectively treat at least some forms of skin cancer. It is known that imiquimod signals to the innate arm of the immune system through the toll-like receptor 7 (TLR7), commonly involved in pathogen recognition. Cells activated by imiquimod via TLR-7 secrete cytokines (primarily interferon-α (INF-α), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α)).
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