Harringtonin

  • Chemical Properties
CAS No. 26833-85-2 Cat. No. BCP04090
Name Harringtonin
Synonyms Alkaloid C from cephalotaxus; NSC124147;NSC 124147;NSC-124147;
Formula C28H37NO9 M. Wt 531.59
  • Biological Activity
Description Harringtonine is found in Cephalotaxuts. It immobilizes initiated ribtosomes, inhibiting protein translation by blocking the ribosomal A site. It suppresses viral replication and protein expression in chikungunya virus infection, inhibits cell growth in actue promyelocytic leukemia cells, and induces apoptosis in leukemia cells.

Structure

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