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CAS No. | 26833-85-2 | Cat. No. | BCP04090 |
Name | Harringtonin | ||
Synonyms | Alkaloid C from cephalotaxus; NSC124147;NSC 124147;NSC-124147; | ||
SMILES | CC(C)(CCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O | ||
Chemical Name | |||
Formula | C28H37NO9 | M. Wt | 531.59 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Harringtonine is found in Cephalotaxuts. It immobilizes initiated ribtosomes, inhibiting protein translation by blocking the ribosomal A site. It suppresses viral replication and protein expression in chikungunya virus infection, inhibits cell growth in actue promyelocytic leukemia cells, and induces apoptosis in leukemia cells. |
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