Rilpivirine
| CAS No. | 500287-72-9 | Cat. No. | BCP03563 |
| Name | Rilpivirine | ||
| Synonyms | R 278474;R-278474;R278474;TMC-278;TMC 278;TMC278; | ||
| Formula | C22H18N6 | M. Wt | 366.42 |
| Description | Rilpivirine shows antiviral activity with EC50 ranging from 0.1 nM to 2 nM against wild-type and selected site-directed single and double mutants of HIV-1. Rilpivirine inhibits viral replication at concentrations at which first-generation NNRTIs could not suppress replication, and produces a high genetic barrier to resistance development. | ||
| Pathways | Microbiology/Virology | ||
| Targets | Reverse Transcriptase HIV | ||
Structure
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