Rilpivirine
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CAS No. | 500287-72-9 | Cat. No. | BCP03563 |
Name | Rilpivirine | ||
Synonyms | R 278474;R-278474;R278474;TMC-278;TMC 278;TMC278; | ||
SMILES | |||
Chemical Name | |||
Formula | C22H18N6 | M. Wt | 366.42 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Rilpivirine shows antiviral activity with EC50 ranging from 0.1 nM to 2 nM against wild-type and selected site-directed single and double mutants of HIV-1. Rilpivirine inhibits viral replication at concentrations at which first-generation NNRTIs could not suppress replication, and produces a high genetic barrier to resistance development. |
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