Tepoxalin
| CAS No. | 103475-41-8 | Cat. No. | BCP23064 |
| Name | Tepoxalin | ||
| Synonyms | ORF-20485; ORF20485; ORF 20485; RWJ-20485; RWJ 20485; RWJ20485; | ||
| Formula | C20H20ClN3O3 | M. Wt | 385.84 |
| Description | Tepoxalin is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis (OA). Tepoxalin has in vivo inhibitory activity against COX-1, COX-2, and 5-LOX in dogs at the current approved recommended dosage.Tepoxalin inhibits inflammation and microvascular dysfunction induced by abdominal irradiation in rats. Tepoxalin enhances the activity of an antioxidant, pyrrolidine dithiocarbamate, in attenuating tumor necrosis factor alpha-induced apoptosis in WEHI 164 cells. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Lipoxygenase | ||
Structure
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