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Tepoxalin Chemical Structure

Tepoxalin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP23064CAS No. :103475-41-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 103475-41-8 Cat. No. BCP23064
Name Tepoxalin
Synonyms ORF-20485; ORF20485; ORF 20485; RWJ-20485; RWJ 20485; RWJ20485;
SMILES CN(C(=O)CCC1=NN(C(=C1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)OC)O
Chemical Name
Formula C20H20ClN3O3 M. Wt 385.84
Purity 98% Storage Store at 4-8°C
Description Tepoxalin is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis (OA). Tepoxalin has in vivo inhibitory activity against COX-1, COX-2, and 5-LOX in dogs at the current approved recommended dosage.Tepoxalin inhibits inflammation and microvascular dysfunction induced by abdominal irradiation in rats. Tepoxalin enhances the activity of an antioxidant, pyrrolidine dithiocarbamate, in attenuating tumor necrosis factor alpha-induced apoptosis in WEHI 164 cells.
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