替沃扎尼
| CAS号 | 475108-18-0 | 货号 | BCP01980 |
| 中文名 | 替沃扎尼 | ||
| 英文名 | Tivozanib | ||
| 中文别名 | |||
| 英文别名 | AV-951;AV951;AV 951; KRN951; KRN 951; KRN-951; | ||
| 分子式 | C22H19ClN4O5 | 分子量 | 454.86 |
| 生物活性 | Tivozanib, also known as KRN951, is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities. Tivozanib binds to and inhibits VEGFRs 1, 2 and 3, which may result in the inhibition of endothelial cell migration and proliferation, inhibition of tumor angiogenesis and tumor cell death. VEGFR tyrosine kinases, frequently overexpressed by a variety of tumor cell types, play a key role in angiogenesis. | ||
| 上下游产品 | 682745-41-1（替沃扎尼盐酸盐一水合物） | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | PDGFR VEGFR | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！