AZ-23

  • Chemical Properties
CAS No. 915720-21-7 Cat. No. BCP01916
Name AZ-23
Synonyms AZ 23;AZ23;
Formula C17H19ClFN7O M. Wt 391.83
  • Biological Activity
Description AZ-23 is a potent, orally bioavailable Trk kinase inhibitor with IC50s of 2 nM (TrkA), 8 nM (TrkB), 24 nM (FGFR1), 52 nM (Flt3), 55 nM (Ret), 84 nM (MuSk), 99 nM (Lck), respectively.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets Trk Receptor 

Structure

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