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CAS No. | 915720-21-7 | Cat. No. | BCP01916 |
Name | AZ-23 | ||
Synonyms | AZ 23;AZ23; | ||
SMILES | CC(C)OC1=NNC(=C1)NC2=NC(=NC=C2Cl)NC(C)C3=NC=C(C=C3)F | ||
Chemical Name | |||
Formula | C17H19ClFN7O | M. Wt | 391.83 |
Purity | 98% | Storage | Store at 4-8°C |
Description | AZ-23 is a potent, orally bioavailable Trk kinase inhibitor with IC50s of 2 nM (TrkA), 8 nM (TrkB), 24 nM (FGFR1), 52 nM (Flt3), 55 nM (Ret), 84 nM (MuSk), 99 nM (Lck), respectively. |
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