Cinacalcet hydrochloride
| CAS No. | 364782-34-3 | Cat. No. | BCP02533 |
| Name | Cinacalcet hydrochloride | ||
| Synonyms | Cinacalcet HCl;Mimpara;Sensipar;AMG-073;AMG 073;AMG073; | ||
| Formula | C22H22F3N.HCl | M. Wt | 393.88 |
| Description | Cinacalcet Hydrochloride is the orally bioavailable hydrochloride salt of the calcimimetic cinacalcet. Cinacalcet increases the sensitivity of calcium-sensing receptors on chief cells in the parathyroid gland to extracellular calcium, thereby reducing parathyroid hormone (PTH) secretion. A reduction in PTH levels inhibits osteoclast activity, which may result in a decrease in cortical bone turnover and bone fibrosis, and normalization of serum calcium and phosphorus levels. In addition, by reducing PTH levels, cinacalcet may reduce PSA levels; PTH appears to raise PSA levels and may increase prostate cancer cell growth. | ||
| Pathways | GPCR/G Protein | ||
| Targets | CaSR | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.