Eltrombopag
CAS No. | 496775-61-2 | Cat. No. | BCP01884 |
Name | Eltrombopag | ||
Synonyms | SB497115; SB-497115; SB 497115; SB497115GR;SB-497115-GR;Revolade; | ||
Formula | C25H22N4O4 | M. Wt | 442.47 |
Description | Eltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production. | ||
Related Products | 496775-62-3(Eltrombopag Olamine) | ||
Pathways | Others Pathway | ||
Targets | Others |
Structure
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