Eltrombopag

  • Chemical Properties
CAS No. 496775-61-2 Cat. No. BCP01884
Name Eltrombopag
Synonyms SB497115; SB-497115; SB 497115; SB497115GR;SB-497115-GR;Revolade;
Formula C25H22N4O4 M. Wt 442.47
  • Biological Activity
Description Eltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.
Related Products 496775-62-3(Eltrombopag Olamine)
Pathways Others Pathway 
Targets Others 

Structure

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