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CAS No. | 496775-61-2 | Cat. No. | BCP01884 |
Related Products | 496775-62-3(Eltrombopag Olamine) | ||
Name | Eltrombopag | ||
Synonyms | SB497115; SB-497115; SB 497115; SB497115GR;SB-497115-GR;Revolade; | ||
SMILES | O=C(C1=CC(C2=CC=CC(N/N=C3C(C)=NN(C4=CC=C(C)C(C)=C4)C/3=O)=C2O)=CC=C1)O | ||
Chemical Name | |||
Formula | C25H22N4O4 | M. Wt | 442.47 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Eltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production. |
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