SSR 146977
| CAS No. | 264618-44-2 | Cat. No. | BCP27720 |
| Name | SSR 146977 | ||
| Synonyms | SSR-146977;SSR146977; | ||
| Formula | C35H42Cl2N4O2 | M. Wt | 621.65 |
| Description | SSR 146977 is a potent and selective NK3 receptor antagonist (Ki values are 0.26 and 19.3 nM in CHO cells expressing the human NK3 and NK2 receptor respectively). Also inhibits senktide-induced inositol monophosphate formation and intracellular calcium mobilization (IC50 = 10 nM). | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | NK Receptor | ||
Structure
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