SSR 146977 New
Data Sheet
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| CAS No. | 264618-44-2 | Cat. No. | BCP27720 |
| Name | SSR 146977 | ||
| Synonyms | SSR-146977;SSR146977; | ||
| SMILES | CN(C)C(=O)NC1(CCN(CC1)CCCC2(CCCN(C2)C(=O)C3=CC=CC=C3)C4=CC(=C(C=C4)Cl)Cl)C5=CC=CC=C5 | ||
| Chemical Name | |||
| Formula | C35H42Cl2N4O2 | M. Wt | 621.65 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SSR 146977 is a potent and selective NK3 receptor antagonist (Ki values are 0.26 and 19.3 nM in CHO cells expressing the human NK3 and NK2 receptor respectively). Also inhibits senktide-induced inositol monophosphate formation and intracellular calcium mobilization (IC50 = 10 nM). | ||
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